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Olga Gielen Selected Research

MRK 560

1/2021PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia.

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Olga Gielen Research Topics

Disease

11Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
04/2022 - 04/2011
9Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
10/2022 - 11/2014
7Leukemia
10/2022 - 06/2012
2Neoplasms (Cancer)
05/2014 - 07/2008
1Hyperplasia
01/2021
1Weight Loss (Weight Reduction)
01/2021
1Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral)
01/2021
1Polyps
05/2014
1Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
05/2014
1Eosinophilia
05/2014
1Leiomyoma (Uterine Fibroids)
05/2014
1Genetic Translocation (Chromosomal Translocation)
07/2008

Drug/Important Bio-Agent (IBA)

5Phosphotransferases (Kinase)IBA
11/2021 - 07/2008
4Pharmaceutical PreparationsIBA
01/2021 - 01/2014
4Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2018 - 07/2008
2DNA (Deoxyribonucleic Acid)IBA
04/2022 - 11/2021
2ruxolitinibIBA
01/2021 - 12/2019
2EltanexorIBA
01/2021 - 11/2020
2Dexamethasone (Maxidex)FDA LinkGeneric
11/2020 - 12/2019
2Janus Kinase 3IBA
01/2018 - 11/2015
2Cytokine Receptors (Cytokine Receptor)IBA
11/2015 - 11/2014
1Poly(ADP-ribose) Polymerase InhibitorsIBA
10/2022
1NucleotidesIBA
04/2022
1Gamma Secretase Inhibitors and ModulatorsIBA
01/2021
1Imatinib Mesylate (Gleevec)FDA Link
01/2021
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2021
1CateninsIBA
01/2021
1MRK 560IBA
01/2021
1Amyloid Precursor Protein Secretases (beta-Secretase)IBA
01/2021
1lambda Spi-1IBA
01/2021
1Doxorubicin (Adriamycin)FDA LinkGeneric
11/2020
1Vincristine (Oncovin)FDA LinkGeneric
11/2020
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2019
1Histone Deacetylases (Histone Deacetylase)IBA
10/2019
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
10/2019
1Messenger RNA (mRNA)IBA
12/2016
1GANT 61IBA
12/2016
1Small Interfering RNA (siRNA)IBA
12/2016
1HhAntag691IBA
12/2016
1Janus Kinase InhibitorsIBA
11/2015
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
05/2014
1Lymphocyte Specific Protein Tyrosine Kinase p56(lck) (p56 lck)IBA
01/2014
1src-Family KinasesIBA
01/2014
1Proteins (Proteins, Gene)FDA Link
01/2014
1bosutinibIBA
01/2014
1Dasatinib (BMS 354825)FDA Link
01/2014
1Nuclear Pore Complex Proteins (Nucleoporins)IBA
07/2008

Therapy/Procedure

1Bone Marrow Transplantation (Transplantation, Bone Marrow)
04/2011